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. 2006 Dec 5;27(5):271–274. doi: 10.1002/clc.4960270506

Reduced quality of life after myocardial infarction in women compared with men

Stefan Agewall 1,, Margareta Berglund 1, Loghman Henareh 1
PMCID: PMC6654191  PMID: 15188941

Abstract

Background: Psychosocial factors have been suggested as risk factors for atherosclerotic disease.

Hypothesis: The purpose of the present study was to examine whether there is a gender difference in quality of life after a myocardial infarction with modern treatment of acute ischemic heart disease.

Methods: In all, 123 men and women aged between 31 and 80 years, and with a hospital‐diagnosed myocardial infarction occurring 1‐‐12 months prior to inclusion, were studied. Minor symptoms evaluation profile (MSEP) was used to estimate quality of life at entry.

Results: Age, hemodynamic data, smoking habits, as well as laboratory data, concomitant cardiovascular disease, and revascularization rate did not differ between men and women. Women had significantly more negative feelings regarding all the estimated dimensions of quality of life (Contentment, Vitality, and Sleep) than did men.

Conclusion: Self‐assessed quality of life after a myocardial infarction was significantly lower among women than among men despite similar age, treatment, and hemodynamic and laboratory data. The causal relationship is however, not known. Further studies are needed to evaluate the underlying mechanism of this observation. This may lead to the development of novel treatment strategies in female patients after a myocardial infarction.

Keywords: quality of life, myocardial infarction, gender

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References

  • 1. Manuck SB, Kaplan JR, Matthews KA: Behavioral antecedents of coronary heart disease and atherosclerosis. Arteriosclerosis 1986; 6: 1–14 [DOI] [PubMed] [Google Scholar]
  • 2. Marmot MG: Stress, social and cultural variations in heart disease. J Psychosom Res 1983; 27: 377–384 [DOI] [PubMed] [Google Scholar]
  • 3. Reed D, McGee D, Yano Y, Feinleib M: Social networks and coronary heart disease among Japanese men in Hawaii. Am J Epidemiol 1983; 117: 384–396 [DOI] [PubMed] [Google Scholar]
  • 4. Berkman LF, Syme SL: Social networks, host resistance, and mortality: A nine‐year follow‐up study of Alameda County residents. Am J Epidemiol 1979; 109: 186–204 [DOI] [PubMed] [Google Scholar]
  • 5. Matsumoto Y, Uyama O, Shimizu S, Michishita H, Mori R, Owada T, Sugita M: Do anger and aggression affect carotid atherosclerosis ? Stroke 1993; 24: 983–986 [DOI] [PubMed] [Google Scholar]
  • 6. Welin L, Tibblin G, Svärdsudd K, Tibblin B, Ander‐Peciva S, Larsson B, Wilhelmsen L: Prospective study of social influences on mortality. The study of men born in 1913 and 1923. Lancet 1985; i: 915–918 [DOI] [PubMed] [Google Scholar]
  • 7. Agewall S, Wikstrand J, Dahlöf C, Fagerberg B: Negative feelings (discontent) predict progress of intima‐media thickness of the common carotid artery in treated hypertensive men at high cardiovascular risk. Am J Hypertens 1996; 9: 545–550 [DOI] [PubMed] [Google Scholar]
  • 8. Agewall S, Wikstrand J, Fagerberg B: Stroke was predicted by dimensions of quality of life in treated hypertensive men. Stroke 1998; 29: 2329–2333 [DOI] [PubMed] [Google Scholar]
  • 9. Cerqueira M: Diagnostic testing strategies for coronary heart disease: Special issues related to gender. Am J Cardiol 1995; 75: 52D–60D [PubMed] [Google Scholar]
  • 10. Wiklund I, Herlitz J, Johansson S, Bengtsson A, Karlsson BW, Persson NG: Subjective symptoms and well‐being differ in men and women after myocardial infarction. Eur Heart J 1993; 14: 1315–1319 [DOI] [PubMed] [Google Scholar]
  • 11. Myocardial infarction redefined : A consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. Eur Heart J 2000; 21: 1502–1513 [DOI] [PubMed] [Google Scholar]
  • 12. Dahlöf C, Dimenäs E, Olofsson B: Documentation of an instrument for assessment of subjective CNS‐related symptoms during cardiovascular pharmacotherapy. Cardiovasc Drug Ther 1989; 3: 919–927 [DOI] [PubMed] [Google Scholar]
  • 13. Dahlöf C: Minor symptoms evaluation (MSE) profile—a questionnaire for assessment of subjective CNS‐related symptoms. Scand J Prim Health Care 1990;(suppl 1): 19–25 [PubMed]
  • 14. Dimenäs E, Wiklund I, Dahlöf C, Lindvall KG, Olofsson B, de Faire U: Differences in the subjective well‐being and symptoms of normotensives, borderline hypertensives and hypertensives. J Hypertens 1989; 7: 885–890 [DOI] [PubMed] [Google Scholar]
  • 15. Colantonio A, Kasi SV, Ostfeld AM: Depressive symptoms and other factors as predictors of stroke in the elderly. Am J Epidemiol 1992; 136: 884–895 [DOI] [PubMed] [Google Scholar]
  • 16. Everson SA, Lynch JW, Chesney MA: Interaction of workplace demands and cardiovascular reactivity in progression of carotid atherosclerosis: Population–based study. Br Med J 1997; 314: 553–558 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17. Lane D, Carroll D, Ring C, Beevers DG, Lip GY: Mortality and quality of life 12 months after myocardial infarction: Effects of depression and anxiety. Psychosom Med 2001; 63: 221–230 [DOI] [PubMed] [Google Scholar]
  • 18. Westin L, Carlsson R, Erhardt L, Cantor‐Graee E, McNeil T: Difference in quality of life in men and women with ischemic heart disease. Scand Cardiovasc J 1999; 33: 160–165 [DOI] [PubMed] [Google Scholar]
  • 19. Maeland JG, Havik OE: Self‐assessment of health before and after a myocardial infarction. Soc Sci Med 1988; 26: 597–605 [DOI] [PubMed] [Google Scholar]

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