Abstract
We present two brothers with anomalous origin of left coronary artery from the right sinus of Valsalva. Screening of other members of the family revealed no coronary artery anomalies. The likelihood of finding such a rare anomaly in two members of a family by chance alone is extremely small; extensive review of the literature found only three other reports of such familial association.
Keywords: familial, coronary anomalies, sinus of Valsalva, left main coronary artery, coronary angiography, interarterial, retroaortic
Full Text
The Full Text of this article is available as a PDF (197.7 KB).
References
- 1. Yamanaka O, Hobbs RE: Coronary artery anomalies in 126,595 patients undergoing coronary arteriography. Cathet Cardiovasc Diagn 1990; 21: 28–40 [DOI] [PubMed] [Google Scholar]
- 2. Alexander RW, Griffith GC: Anomalies of the coronary arteries and their clinical significance. Circulation 1956; 14: 800–805 [DOI] [PubMed] [Google Scholar]
- 3. Deligonul U, Kern MJ, Roth R: Angiographic data In The Cardiac Catheterization Handbook (3rd Ed.) (Ed. Kern M.), pp. 312–313. St. Louis: Mosby, 1999. [Google Scholar]
- 4. Taylor AJ, Rogan KM, Virmani R: Sudden cardiac death associated with isolated congenital coronary artery anomalies. J Am Coll Cardiol 1992; 20: 640–647 [DOI] [PubMed] [Google Scholar]
- 5. Burke AP, Farb A, Virmani R, Goodin J, Smialek JE: Sports‐related and non‐sports‐related sudden cardiac death in young adults. Am Heart J 1991; 121: 568–575 [DOI] [PubMed] [Google Scholar]
- 6. Maron BJ, Shirani J, Poliac LC, Mathenge R, Roberts WC, Mueller FO: Sudden death in young competitive athletes. Clinical, demographic, and pathological profiles. J Am Med Assoc 1996; 276: 199–204 [PubMed] [Google Scholar]
- 7. Horan PG, Murtagh G, McKeown PP: Single coronary artery: A familial clustering. Heart 2003; 89: e27 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 8. Bunce NH, Rahman SL, Keegan J, Gatehouse PD, Lorenz, CH , Pennell DJ: Anomalous coronary arteries: Anatomic and functional assessment by coronary and perfusion cardiovascular magnetic resonance in three sisters. J Cardiovasc Magn Reson 2001; 3 (4): 361–369 [DOI] [PubMed] [Google Scholar]
- 9. Rowe L, Carmody TJ, Askenazi J: Anomalous origin of the left circumflex coronary artery from the right aortic sinus: A familial clustering. Cathet Cardiovasc Diagn 1993; 29: 277–278 [DOI] [PubMed] [Google Scholar]
- 10. Leon AS, Bloor CM: Quantitative analysis of coronary artery inheritance. J Hered 1968; 59 (1): 48–52 [DOI] [PubMed] [Google Scholar]