Abstract
Current protocols for risk stratification of patients with acute chest pain syndromes rely on clinical parameters and are oriented toward identification of patients at high risk for adverse cardiac events; however, this paradigm for risk stratification does not adequately address the observation that adverse cardiac events are relatively uncommon in this population. In an era of cost containment, consideration also should be given to identification of patients at low risk for adverse cardiac events, who may be safely discharged without expensive inpatient hospitalization.
Keywords: unstable angina, chest pain, risk stratification, echocardiography
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References
- 1. Braunwald E, Jones RH, Mark DB, Brown J, Brown L, Cheitlin MD. Concannon CA, Cowan M, Edwards C, Fuster V, Goldman L, Green LA, Grines CL, Lytle BW, McCauley KM, Mushlin AI, Rose GC, Smith EE, Swain JA, Topol EJ, Willerson JT: Diagnosing and managing unstable angina. Circulation 1994; 90: 613–622 [DOI] [PubMed] [Google Scholar]
- 2. Braunwald E, Brown J, Brown L, Cheitlin MD, Coneannon CA, Cowan M, Edwards C, Fuster V, Goldman L, Green LA, Grines CL, Lytle BW, McCauley KM, Mushlin AI, Rose GC, Smith EE, Swain JA, Topol EJ, Willerson JT: Diagnosing and managing unstable angina: Quick reference guide for clinicians, number 10. AHCPR Research Publication No. 94‐0603, Rockville, Md. U.S. Department of Health and Human Services. Public Health Service, Agency for Health Care Policy and Research and National Heart, Lung, and Blood Institute. March 1994.
- 3. Calvin JE, Klein LW, VandenBerg BJ, Meyer P, Condon JV, Snell RJ, Ramirez‐Morgan LM, Parrillo JE: Risk stratification in unstable angina: Prospective validation of the Braunwald criteria. J Am Med Assoc 1995; 273: 136–141 [PubMed] [Google Scholar]
- 4. Lee TH, Cook EF, Weisberg MG, Sargent RK, Wilson C, Goldman L: Acute chest pain in the emergency room: Identification of low risk patients. Arch Intern Med 1985; 45: 65–69 [PubMed] [Google Scholar]
- 5. Lee TH, Juarez G, Cook EF, Weisberg MC, Rouan GW, Brand DA, Goldman L: Ruling out acute myocardial infarction: A prospective multicenter validation of a 12‐hour strategy for patients at low risk. N Engl J Med 1991; 324: 1239–1246 [DOI] [PubMed] [Google Scholar]
- 6. Goldman L, Cook EF, Johnson PA, Brand DA, Rouan GW, Lee TH: Prediction of the need for intensive care in patients who come to emergency departments with acute chest pain. N Engl J Med 1996; 334: 1498–1504 [DOI] [PubMed] [Google Scholar]
- 7. Rizik DG, Healy S, Margulis A, Vandam D, Bakalyar D, Timmis G, Grines C, O'Neill WW, Schreiber TL: A new clinical classification for hospital prognosis of unstable angina pectoris. Am J Cardiol 1995; 75: 993–997 [DOI] [PubMed] [Google Scholar]
- 8. Baxt WG, Skora J: Prospective validation of artificial neural network trained to identify acute myocardial infarction. Lancet 1996; 347: 12–15 [DOI] [PubMed] [Google Scholar]
- 9. Lewis WR, Amsterdam EA: Evaluation of the patient with “rule out myocardial infarction.” Arch Intern Med 1996; 156: 41–45 [PubMed] [Google Scholar]
- 10. Katz DA, Griffith JL, Beshansky JR, Selker HP: The use of empiric clinical data in the evaluation of practice guidelines for unstable angina. J Am Med Assoc 1996; 276: 1568–1574 [PubMed] [Google Scholar]
- 11. Visser CA, David GK. Kan G, Romijn KH, Meltzer RS, Koolen JJ, Dunning AJ: Two‐dimensional echocardiography during percutaneous transluminal coronary angioplasty. Am Heart J 1986; 111: 1035–1041 [DOI] [PubMed] [Google Scholar]
- 12. Hauser AM, Ganadharan V, Ramos RG, Gordon S, Timmis GC: Sequence of mechanical, electrocardiographic, and clinical effects of repeated coronary artery occlusion in human beings: Echocardiographic observations during coronary angioplasty. J Am Coll Cardiol 1985; 5: 193–197 [DOI] [PubMed] [Google Scholar]
- 13. Nixon JV, Brown CV, Smitheren TC: Identification of transient and persistent wall motion abnormalities in patients with unstable angina by two‐dimensional echocardiography. Circulation 1982; 65: 1497–1503 [DOI] [PubMed] [Google Scholar]
- 14. Oh JK, Meloy TD, Seward JB: Echocardiography in the emergency room: Is it feasible, beneficial, and cost‐effective? Echocardiography 1995; 12: 163–170 [DOI] [PubMed] [Google Scholar]
- 15. Fleischmann KE, Goldman L, Robiolio PA, Lee RT, Johnson PA, Cook EF, Lee TH: Echocardiographic correlates of survival in patients with chest pain. J Am Coll Cardiol 1994; 23: 1390–1396 [DOI] [PubMed] [Google Scholar]
- 16. Sabia P, Abbott RD, Afrookteh A, Keller MW, Touchstone DA, Kaul S: Importance of two‐dimensional echocardiographic assessment of left ventricular systolic function in patients presenting to the emergency room with cardiac‐related symptoms. Circulation 1991; 84: 1615–1624 [DOI] [PubMed] [Google Scholar]
- 17. Touchstone DA, Beller GA, Nygaard TW, Tedesco C, Kaul S: Effects of successful intravenous reperfusion therapy on regional myocardial function and geometry in humans: A tomographic assessment using two‐dimensional echocardiography. J Am Coll Cardiol 1989; 13: 1506–1513 [DOI] [PubMed] [Google Scholar]
- 18. Akinboboye O, Sumner J, Gopal A, King D, Shen Z, Bardfeld P, Blanz L, Brown EJ: Visual estimation of ejection fraction by two‐dimensional echocardiography: The learning curve. Clin Cardiol 1995; 18: 726–729 [DOI] [PubMed] [Google Scholar]
- 19. Starling MR, Crawford MH, Sorensen SG, Levi B, Richards KL, O'Rourke RA : Comparative accuracy of apical biplane cross‐sectional echocardiography and gated equilibrium radionuclide angiography for estimating left ventricular size and performance, Circulation 1981; 63: 1075–1084 [DOI] [PubMed] [Google Scholar]
- 20. Bland JM, Altman DG: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1: 307–310 [PubMed] [Google Scholar]
- 21. The Multicenter Post Infarction Research Group : Risk stratification and survival after myocardial infarction. N Engl J Med 1983; 309: 331–336 [DOI] [PubMed] [Google Scholar]
- 22. Sanz G, CastaZer A, Betriu A, MagriZa J, Roig E, Coll S, Pare JC, Navarro‐López F: Determinants of prognosis in survivors of myocardial infarction infarction. N Engl J Med 1982; 306: 1065–1070 [DOI] [PubMed] [Google Scholar]
- 23. Nishimura RA, Reeder GS, Miller FA, Ilstrup DM, Shub C, Seward JB, Tajik AJ: Prognostic value of pre‐discharge echocardiogram after acute myocardial infarction. Am J Cardiol 1984; 53: 429–432 [DOI] [PubMed] [Google Scholar]
- 24. Tcheng JE, Jackman JD, Nelson CL, Gardner LH, Smith LR, Rankin JS, Califf RM, Stack RS: Outcome of patients sustaining acute ischemic mitral regurgitation during myocardial infarction. Ann Intern Med 1992; 117: 18–24 [DOI] [PubMed] [Google Scholar]
- 25. Lehman KG, Francis CK, Dodge HT, and the TIMI Study Group : Mitral regurgitation in early myocardial infarction. Ann Intern Med 1992; 117: 10–17 [DOI] [PubMed] [Google Scholar]
- 26. Trippi JA, Lee KS, Kopp G, Nelson D., Kovacs R : Emergency echocardiography telemedicine: An efficient method to provide 24‐hour consultative echocardiography. J Am Coll Cardiol 1996; 27: 1748–1752 [DOI] [PubMed] [Google Scholar]