In the Introduction, there is an error in the third sentence of the third paragraph. The correct sentence is: As a result, food challenges are often under performed, leading to an overdiagnosis of FA [9].
There is an error in Table 6. The vales in column 4 "Average Accuracy" are incorrect. The publisher apologizes for the error. Please see the correct Table 6 here.
Table 6. Average hidden data accuracy across a large number of dataset permutations.
| Number | Signature | n | Average Accuracy | AUROC | 95% CI for Accuracy |
|---|---|---|---|---|---|
| 1 | 12-CpG #1 | 200 | 95.313 | 0.98328 | (94.175, 96.451) |
| 2 | 12-CpG #2 | 200 | 95.625 | 0.98531 | (94.483, 96.767) |
| 3 | 18-CpG | 200 | 93.438 | 0.98047 | (92.216, 94.734) |
This table shows the average accuracy and AUROC across n randomized hidden test cohorts. The 95% Confidence Interval for accuracy is also shown and provides an estimate for the true population accuracy of each classifier on similar cohorts of patients.
Reference
- 1.Alag A (2019) Machine learning approach yields epigenetic biomarkers of food allergy: A novel 13-gene signature to diagnose clinical reactivity. PLoS ONE 14(6): e0218253 10.1371/journal.pone.0218253 [DOI] [PMC free article] [PubMed] [Google Scholar]
