Fig 1.

Tumor volumes at diagnosis and resection based on resection approach and administration of neoadjuvant chemotherapy. (A) Tumor volumes based on resection approach for all tumors at diagnosis and resection. (B) Tumor volumes at diagnosis and resection based on operative approach for all TV <100 mL at resection. (C) Reduction in TV with neoadjuvant chemotherapy from diagnosis to resection based on approach. Boxes represent interquartile range (IQR) with whiskers spanning to 1.5*IQR. Horizontal line within box represents median. Dots represent values outside of 1.5*IQR. Significance (P values) was assessed by Wilcoxon rank sum test and Wilcoxon matched-paired signed-rank test.