Table 5.
Early detection of embryonal tumors.
| MIS | Open TV <100 mL | Open TV >100 mL | |
|---|---|---|---|
| Neuroblastic tumors | |||
| Opsoclonus-myoclonus ataxia | 3 | 2 | 0 |
| VIPoma | 1 | 0 | 0 |
| Prenatal ultrasound | 2 | 0 | 0 |
| Total | 6/20 (30%) | 2/41 (5%) | 0/23 (0%) |
| Wilms tumor | |||
| DHPLN | 1 | 0 | 0 |
| Beckwith-Wiedemann Syndrome | 1 | 2 | 0 |
| WAGR | 0 | 1 | 0 |
| Hemihypertrophy | 0 | 1 | 0 |
| Total | 2/2 (100%) | 4/14 (29%) | 0/50 (0%) |
| Hepatoblastoma | |||
| Hemihypertrophy | 0 | 1 | 0 |
| Beckwith-Wiedemann Syndrome | 0 | 1 | 0 |
| Total | 0/0 (n/a) | 2/10 (20%) | 0/8 (0%) |
| All tumors | |||
| Predisposition/Paraneoplastic/Prenatal | 8/24 (33%) | 8/68 (12%) | 0/82 (0%) |
Note: Category for “all tumors” includes rhabdomyosarcoma even though no special circumstances are noted in this group. In comparing proportion of early detection cases between MIS and Open TV <100 ml, P = .017.
VIP, vasoactive intestinal polypeptide; DHPLN, diffuse hyperplastic perilobar nephroblastomatosis; WAGR, Wilms tumor, aniridia, genitourinary abnormalities, and mental retardation.