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Sequence of interventions associated with neoadjuvant rectal cancer clinical trial (NCT03300544) incorporating TVEC.
#Patients with inadequate archival tissue for integrated biomarker analysis
^As part of pre-surgical evaluation or at a corresponding time point in patients not undergoing surgery
+Dose escalation will be done using a 3+3 design for a total of 15 patients that will be treated at MTD
TVEC = talimogene laherparepvec
