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Protective efficacy of immunization with T.gondii VLPs. Naïve or immunized mice (n = 5) were orally infected with 450 T. gondii ME49 cyst after boost immunization. Mice were monitored for 60 days to observe changes in body weight (A) and survival (B) after challenge infection. Upon challenge infection, all immunized mice survived and ROP(4 + 13) VLPs immunization showed the least weight loss, whereas all naïve challenge mice showed rapid weight loss and died on day 35.
