Figure 3.
CPTH2 primarily inhibits CTG clade Candida species. (a) Spot dilution assay of C. albicans, S. cerevisiae, and C. glabrata on YPD plates. Only C. albicans shows clear growth inhibition at 50 µM CPTH2. (b) Spot dilution assays of different Candida species on plates containing either CPTH2 or caspofungin (CASP). CTG clade membership of the respective species is indicated on the right. (c) Liquid growth inhibition assay in YPD medium. Fungal strains were incubated with the indicated concentrations of CPTH2 for 24 h prior to OD600 measurement. Data shown are mean ± sd of four biological replicates.