Figure 8.

(Inset) Time evolution of r, the distance from the center of the large “rigid” sphere with radius $b_{\mathrm{S}}=20$ nm to the center of the confinement sphere. (Main) Plot of $Q_{\mathrm{S}}(r)$, the enrichment in the probability of finding the large sphere at distance r from the center of the confinement sphere, for the “rigid” case (dashed blue line) and the “soft” case (solid red line). $Q_{\mathrm{S}}(r)$ is constant and equal to 1 (dot-dashed horizontal gray line) if the probability of finding the large sphere is uniform inside the confinement sphere. Time is expressed in units of ms and r in units of nm. The effective volume fraction occupied by the $N=1499$ crowders of radius $b=6.5$ nm is $\rho =0.52$.