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The effect of FRG on TNF-α and IL-6 production in bone marrow-derived macrophages (BMDMs). Primary BMDMs were isolated from mice and differentiated for six days. Media was collected for TNF-α and IL-6 analysis 24 h after FRG treatment. (A) TNF-α and (B) IL-6 levels were measured as described in the Materials and Methods section. *** p < 0.001, significant difference between FGR treated group and control (n = 3).
