Table 5.
Variables | Test (n = 41) | Placebo (n = 37) | p-Value * | |
---|---|---|---|---|
Fasting glucose | Baseline | 93.49 ± 10.38 | 93.49 ± 9.51 | 0.9995 |
(mg/dL) | 6 weeks | 95.34 ± 9.37 | 91.92 ± 8.23 | 0.092 |
12 weeks | 93.00 ± 10.33 | 94.38 ± 10.44 | 0.560 | |
Δ6 week-baseline | 1.85 ± 8.66 | –1.57 ± 9.28 | 0.096 | |
Δ12 week-baseline | –0.49 ± 8.18 | 0.89 ± 11.20 | 0.534 | |
Fasting insulin | Baseline | 8.45 ± 4.93 | 9.51 ± 5.62 | 0.377 |
(mIU/L) | 6 weeks | 9.27 ± 5.93 | 8.94 ± 4.83 | 0.791 |
12 weeks | 8.03 ± 4.04 | 9.65 ± 4.81 | 0.110 | |
Δ6 week-baseline | 0.82 ± 3.51 | –0.57 ± 5.51 | 0.194 | |
Δ12 week-baseline | –0.42 ± 4.65 | 0.14 ± 5.14 | 0.617 | |
HOMA-IR | Baseline | 1.98 ± 1.25 | 2.24 ± 1.45 | 0.396 |
6 weeks | 2.24 ± 1.56 | 2.08 ± 1.24 | 0.611 | |
12 weeks | 1.88 ± 1.05 | 2.31 ± 1.31 | 0.116 | |
Δ6 week-baseline | 0.26 ± 0.94 | –0.17 ± 1.40 | 0.124 | |
Δ12 week-baseline | –0.10 ± 1.20 | 0.06 ± 1.31 | 0.567 | |
HOMA-β | Baseline | 94.52 ± 94.34 | 120.53 ± 70.79 | 0.176 |
6 weeks | 104.39 ± 56.21 | 113.28 ± 56.87 | 0.490 | |
12 weeks | 104.83 ± 61.57 | 115.35 ± 59.39 | 0.446 | |
Δ6 week-baseline | 9.87 ± 83.36 | –7.25 ± 73.65 | 0.342 | |
Δ12 week-baseline | 10.31 ± 91.36 | –5.18 ± 76.32 | 0.422 | |
hs-CRP | Baseline | 1.36 ± 1.96 | 2.14 ± 5.79 | 0.442 |
(mg/L) | 6 weeks | 1.06 ± 1.25 | 1.61 ± 2.94 | 0.298 |
12 weeks | 1.06 ± 0.91 | 1.13 ± 0.98 | 0.722 | |
Δ6 week-baseline | –0.30 ± 2.10 | –0.53 ± 6.46 | 0.839 | |
Δ12 week-baseline | –0.30 ± 1.79 | –1.00 ± 5.75 | 0.482 | |
Total cholesterol | Baseline | 190.37 ± 28.98 | 190.03 ± 36.68 | 0.964 |
(mg/dL) | 6 weeks | 190.76 ± 26.02 | 196.22 ± 33.84 | 0.424 |
12 weeks | 191.51 ± 30.39 | 199.46 ± 36.02 | 0.294 | |
Δ6 week-baseline | 0.39 ± 19.05 | 6.19 ± 16.47 ** | 0.157 | |
Δ12 week-baseline | 1.15 ± 17.44 | 9.43 ± 20.94 ** | 0.061 | |
LDL | Baseline | 112.95 ± 27.99 | 112.81 ± 34.57 | 0.985 |
(mg/dL) | 6 weeks | 116.44 ± 26.48 | 118.73 ± 31.15 | 0.727 |
12 weeks | 114.27 ± 28.81 | 119.81 ± 32.60 | 0.428 | |
Δ6 week-baseline | 3.49 ± 14.99 | 5.92 ± 17.13 ** | 0.507 | |
Δ12 week-baseline | 1.32 ± 13.64 | 7.00 ± 21.06 | 0.168 | |
HDL | Baseline | 56.59 ± 10.97 | 57.19 ± 12.51 | 0.821 |
(mg/dL) | 6 weeks | 55.80 ± 11.12 | 56.78 ± 12.58 | 0.716 |
12 weeks | 56.66 ± 11.32 | 57.84 ± 12.73 | 0.666 | |
Δ6 week-baseline | –0.78 ± 7.12 | –0.41 ± 5.36 | 0.795 | |
Δ12 week-baseline | 0.07 ± 6.57 | 0.65 ± 7.04 | 0.710 | |
Triglyceride | Baseline | 125.22 ± 123.37 | 121.81 ± 83.08 | 0.886 |
(mg/dL) | 6 weeks | 112.41 ± 64.58 | 118.24 ± 65.10 | 0.693 |
12 weeks | 113.56 ± 87.94 | 129.30 ± 83.00 | 0.420 | |
Δ6 week-baseline | –12.80 ± 79.59 | –3.57 ± 56.33 | 0.553 | |
Δ12 week-baseline | –11.66 ± 79.86 | 7.49 ± 49.92 | 0.204 |
Data are presented as mean ± standard deviation. * p-values were calculated using an independent t-test. HOMA-IR, homeostasis model analysis-insulin resistance; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; HDL, high-density lipoprotein. ** were represented as having p-values < 0.05 in the paired t-test for comparison within-group differences.