Table 3.
Variable | HMF Group (n = 96) |
BMF Group (n = 96) |
p-Value |
---|---|---|---|
Median (IQR) | Median (IQR) | ||
Hierarchical structure of endpoints | |||
Growth velocity (g/kg/d) birth to 37+0 weeks | 15.2 (14.2, 16.7) | 15.6 (13.9, 16.7) | n.s. |
Growth velocity (g/kg/d) fortifier introduction to 32+0 weeks | 16.5 (14.5, 19.1) | 18.9 (15.3, 21.3) | 0.009 |
Growth velocity (g/kg/d) birth to fortifier introduction | 13.5 (7.4, 16.8) | 10.7 (4.8, 15.3) | 0.09 |
Growth velocity (g/kg/d) birth to 32+0 weeks | 15.3 (14.0, 17.7) | 15.1 (13.6, 17.0) | n.s. |
Growth velocity (g/kg/d) 32+0 to 37+0 weeks | 15.5 (13.2, 17.2) | 15.9 (13.9, 17.7) | n.s. |
32+0 weeks of gestational age | |||
weight (g) | 1442 (1267, 1580) | 1430 (1240, 1598) | n.s. |
weight (zscore) | −1.0 (−1.5, −0.7) | −1.1 (−1.5, −0.6) | n.s. |
length increase (cm/week) | 1.0 (0.7, 1.3) | 0.9 (0.6, 1.3) | n.s. |
length (cm) | 38.0 (36.0, 39.4) | 38.0 (36.7, 39.5) | n.s. |
length (zscore) | −2.1 (−2.9, −1.5) | −2.1 (−2.6, −1.5) | n.s. |
head circumference increase (cm/week) | 0.6 (0.4, 0.8) | 0.6 (0.4, 0.8) | n.s. |
head circumference (cm) | 26.5 (25.3, 27.5) | 26.6 (25.5, 27.5) | n.s. |
head circumference (zscore) | −2.0 (−2.8, −1.5) | −2.0 (−2.0, −1.4) | n.s. |
37+0 weeks of gestational age | |||
weight (g) | 2500 (2136, 2722) | 2427 (2155, 2722) | n.s. |
weight (zscore) | −1.0 (−1.8, −0.6) | −1.2 (−1.8, −0.6) | n.s. |
length gain (cm/week) | 1.1 (1.0, 1.3) | 1.1 (0.9, 1.2) | n.s. |
length (cm) | 44.0 (43.0, 45.5) | 44.5 (43.0, 46.0) | n.s. |
length (zscore) | −1.9 (−2.3, −1.2) | −1.7 (−2.3, −1.0) | n.s. |
head circumference gain (cm/week) | 0.8 (0.7, 0.9) | 0.8 (0.7, 0.8) | n.s. |
head circumference (cm) | 31.2 (30.0, 32.0) | 31.5 (30.5, 32.5) | n.s. |
head circumference (zscore) | −1.3 (−2.0, −0.9) | −1.2 (−1.7, −0.6) | n.s. |
HM = human milk, HMF = human milk based fortifier, BMF = bovine based human milk fortifier; Mann-Whitney U test.