Table 7.
Study | HMF Group | BMF Group | p- Value | Method | Timeframe |
---|---|---|---|---|---|
Present study | n = 96 | n = 96 | n.s. | Patel | Birth to 37+0 |
BW, median (IQR) | 752 (659, 893) | 773 (650, 890) | |||
GV, median (IQR) | 15.2 (14.2, 16.7) | 15.6 (13.9, 16.7) | |||
Sullivan et al. [11] | n = 67 | n = 69 | n.s. | Daily weights | *1 |
BW, mean (SD) | 14.2 (11.9, 15.8) | 15.1 (12.8, 17.0) | |||
GV, median (IQR) | 945 (± 202) | 922 (± 197) | |||
Colacci et al. [26] | n = 39 | n = 46 | n.s. | Patel | Birth to discharge |
BW, mean (SD) | 783 (± 143) | 770 (± 137) | |||
GV, mean (SD) | 13.1 (± 4.0) | 12.1 (± 5.2) | |||
Hair et al. 2013 [29] | n = 104 | - | - | Daily weights | Birth to discharge |
BW, mean (SD) | 913 (±182) | ||||
GV, mean (SD) | 24.8 (± 5.4) | ||||
Huston et al. [16] *2 | n = 94 | n = 111 | - | Patel | Birth to discharge |
BW, mean (SD) | 904 (± 200) | 959 (±174) | |||
GV, mean (SD) | 13.6 (± 1.6) | 14.1 (± 1.8) | |||
Assad et al. [12] | n = 87 | n = 127 | n.s. | Two-point average | Birth to discharge |
BW, range | 490–1700 g | 490–1700 g | |||
GV, mean (SD) | 11.6 (± 2.7) | 11.6 (± 2.5) |
*1) birth to earliest of the following milestones: 91 days of age, discharge from hospital, or attainment of 50% oral feedings (i.e., four complete oral feedings per day), *2) birth until 36 weeks or weaned from fortifier (whichever occurred first), transferred to a nonstudy institution, removed from the study, or death; HM = human milk, HMF = human milk based fortifier, BMF = bovine based human milk fortifier, GV = growth velocity, BW = birthweight, IQR = interquartile range, SD = Standard Deviation.