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Imatinib therapy increases the proportion and function of NK cells. NK cells were characterized by flow analysis and functional assays. Imatinib-treatment significantly increases the proportion of NK cells from lymphocytes (a), as well as increase their responsiveness to K562-stimulation measured by degranulation (b-c). Non-parametric Wilcoxon signed-ranked test was performed to find the difference in functional assay at different timepoint and data are presented as boxplots.
