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. 2019 Jun 27;140(6):470–486. doi: 10.1161/CIRCULATIONAHA.118.039107

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© 2019 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 2. — Percent median (Q1–Q3) change from baseline. Percent median (Q1–Q3) change from baseline in (A) triglycerides, (B) absolute median triglyceride levels, and percent LSM (SE) change from baseline in (C) VLDL-C, (D) LDL-C, and (E) HDL-C in subjects with elevated triglycerides and LDL-C (multiple ascending dose study). HDL-C indicates high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; LSM, least-squares mean; Q2W, every 2 weeks; Q4W, once every 4 weeks; QW, once per week; and VLDL-C, very low-density lipoprotein cholesterol.