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. 2019 Jan 4;155(1):246. doi: 10.1016/j.chest.2018.11.012

Errors in Table 1 in: Tracheobronchopathy From Inhaled Corticosteroids

PMCID: PMC6688976  PMID: 30616735

The authors have reported to CHEST errors in Table 1 in their article, “Tracheobronchopathy From Inhaled Corticosteroids” (Chest. 2017;152[6]:1296-1305).

  • The table title should have reflected that the table’s intent was not to provide strict dose equivalence but to act as a guide for prescribing physicians to highlight what should be considered a “high-dose” inhaled corticosteroid.

  • There were errors in doses for beclometasone dipropionate, budesonide, mometasone furoate, and triamcinolone acetonide.

The corrected table appears below. The online article has been corrected.

Table 1.

Corticosteroids for Adults: Estimated Clinical Comparability (μg)a

Inhaled Corticosteroid Low Medium High
Beclometasone dipropionate (HFA) 100-200 >200-400 >400
Budesonide (DPI) 200-400 >400-800 >800
Ciclesonide (HFA) 80-160 >160-320 >320
Flunisolideb 80-160 >160-320 >320
Fluticasone furoate (DPI) 100 NA 200
Fluticasone propionate (DPI) 100-250 >250-500 >500
Fluticasone propionate (HFA) 100-250 >250-500 >500
Mometasone furoate 110-220 >220-440 >440
Triamcinolone acetonide 400-1,000 >1,000-2,000 >2,000

DPI = dry powder inhaler; HFA = hydrofluoroalkane propellant; NA = not available.

a

Modified from Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2017. https://ginasthma.org/wp-content/uploads/2016/01/wms-GINA-2017-main-report-tracked-changes-for-archive.pdf.

b

Linezolid inhaler has been used as a stand-alone inhaled corticosteroid in the past with varying doses for patients with asthma. Higher doses as indicated in this chart may contribute to bronchopathy described in this article, and the aim is to bring this issue to light for patients who may have already been exposed previously.


Articles from Chest are provided here courtesy of American College of Chest Physicians

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