Table 5.

Continuous PTH Stimulated Similar PGE₂ (nM) Accumulation in the Culture Medium of WT and SAA3 KO BMSCs

Days	WT		SAA3 KO
	Vehicle	PTH	Vehicle	PTH
0–3	Und	2.84 ± 0.39	Und	2.93 ± 0.69
3–7	Und	9.42 ± 1.83a	Und	10.34 ± 2.23b
7–10	Und	5.40 ± 0.58	Und	5.01 ± 0.82
10–14	Und	1.45 ± 0.12	Und	1.23 ± 0.14
14–18	Und	Und	Und	Und
18–21	Und	Und	Und	Und

BMSCs were treated with vehicle or PTH (10 nM). Medium was collected at every medium change and assessed for PGE₂ by ELISA. Data are means ± SEM for n = 3 independent samples.

Abbreviation: Und, undetectable.

^a P < 0.05, significantly different from days 0 to 3, determined by one-way ANOVA, post hoc Bonferroni pairwise multiple comparisons.

^b P < 0.01, significantly different from days 0 to 3, determined by one-way ANOVA, post hoc Bonferroni pairwise multiple comparisons.