Femurs from 8-week-old male Bmal1f/+.Ctsk-cre and Bmal1f/f.Ctsk-cre littermates were analyzed by microCT. (A) Trabecular BV/TV, (B) cortical thickness. Subsequently, a three-way analysis of 12-week-old male Bmal1f/f, Bmal1f/+.Ctsk-cre and Bmal1f/f.Ctsk-cre mice was performed comparing (C) trabecular bone parameters, (D) trabecula BMD, (E) cortical thickness, and (F) cortical BMD. Bars are mean and SD; n=8-10 animals per group. There were no statistically significant differences between groups by Student’s t test (A, B) or one-way ANOVA (C-F).