Video 1. Illustration of the DoHM interactions in the Mcm2-7 double hexamer (Abid Ali et al., 2017).

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DOI: 10.7554/eLife.45538.020

The DoHM of Mcm4 (green), the region of Mcm7 that interacts with the DoHM (light blue), and the region of Mcm5 from the opposite hexamer that interacts with the DoHM (yellow) are all shown in space filling representation. The remainder of the structure is shown as a ribbon structure with Mcm6 in orange, Mcm2 in magenta, and Mcm3 in dark blue. Note that there are two DoHM-involved interfaces that are located on opposite sides of the Mcm2-7 double hexamer.