Table 1.
Baseline characteristics (unweighted and weighted) of the DCCT subcohort (n = 518) versus the full DCCT cohort (n = 1,441), and the baseline summaries of the three biomarkers
| Unweighted | Weighted* | Full cohort | |
|---|---|---|---|
| Age (years) | 27 (22, 32) | 27 (21, 32) | 27 (22, 32) |
| Diabetes duration (months) | 55 (30, 115) | 50 (29, 107) | 51 (28, 109) |
| AER (mg/24 h) | 11.5 (7.2, 18.7) | 11.5 (7.2, 18.7) | 11.5 (7.2, 18.7) |
| eGFR (mL/min/1.73 m2) | 124.8 (117.9, 133.1) | 124.9 (117.9, 133.9) | 125 (118, 134) |
| BMI (kg/m2) | 23.4 (21.6, 25.3) | 23.3 (21.5, 25.3) | 23.3 (21.5, 25.2) |
| Triglycerides (mg/dL) | 70 (54, 93) | 69 (54, 91) | 70 (55, 94) |
| LDL (mg/dL) | 105 (88, 126) | 104 (87, 124) | 107 (91, 127) |
| HDL (mg/dL) | 48 (42, 57) | 50 (42, 57) | 49 (42, 57) |
| SBP (mmHg) | 114 (108, 122) | 114 (108, 122) | 114 (108, 122) |
| Diastolic blood pressure (mmHg) | 74 (68, 80) | 74 (68, 80) | 72 (68, 80) |
| Pulse (bpm) | 76 (68, 84) | 76 (68, 84) | 76 (68, 84) |
| HbA1c (%; mmol/mol) | 8.6 (7.6, 9.8); 70 (60, 84) | 8.5 (7.6, 9.8); 69 (60, 84) | 8.7 (7.8, 9.9); 72 (62, 85) |
| Treatment group (% intensive) | 46.3 | 48.7 | 49.3 |
| Cohort (% primary) | 45.2 | 50.0 | 50.4 |
| Sex (% male) | 52.3 | 52.9 | 52.8 |
| Smoking (%) | 19.3 | 18.4 | 18.5 |
| AGE-LDL-IC (mg/L) | 6.4 (2.6, 12) | 5.8 (2.5, 10.8) | |
| MDA-LDL-IC (mg/L) | 107.3 (42.7, 195.9) | 98.5 (37.4, 185.9) | |
| oxLDL-IC (mg/L) | 161.7 (88.6, 295.3) | 149.4 (80.8, 265.9) |
Data are median (quartile 1, quartile 3) unless otherwise indicated.
*With weights based on the joint distribution of the complications and further adjusted for sex and cohort.