Figure 1.

Overall experimental design. Days are identified as yellow squares broken up into five periods of one week. Single severe TBI (s-sTBI; orange squares), single mild TBI (s-mTBI; gray squares) and repeated mild TBI (r-mTBI; blue squares) are shown on the days of the respective injuries. Neurological severity scores (NSS; red squares) were recorded on the second day of each week following the respective injuries. MRI (green squares) was collected at the end of the first week and at the end of the fourth week, respectively. Post mortem MRIs (black squares) were conducted during week 5 following perfusion (white squares).