Table 2.
Sham | s-mTBI | r-mTBI | s-sTBI | |||
---|---|---|---|---|---|---|
Time post -injury |
1 week | 4 weeks | 4 weeks | 4 weeks | ||
Animals / group | 3 | 5 | 7 | 6 | 4 | |
Calcification,# of animals | 0 | 0 | 3 (43%) | 4 (67%) | 2 (50%) | |
Histology+ | # sections | 0 | 0 | 2±2 | 4±2 | 2±1 |
MRI+ | 0 | 0 | 3 (50%) | 4 (67%) | 1 (25%) | |
MRI− | 0 | 0 | 0 | 0 | 1 (25%) | |
MRI+/− | 0 | 0 | 3 (50%) | 4 (67%) | 2 (50%) | |
Histology− | MRI+ | 0 | 2 (40%) | 0 | 1 (17%) | 0 |
MRI− | 3 (100%) | 3 (60%) | 4 (67%) | 1 (17%) | 2 (100%) |
Histology+ and histology− indicate finding or absence of calcium deposits on Alizarin red sections. MRI+ and MRI− indicate finding or absence of calcium deposits on susceptibility maps. “# sections” lists average and standard deviation of the number of sections on which calcium was observed. Stated percentages indicated the fraction with respect to analyzable susceptibility maps (cf. Table 1) except for the total number of animals (# of animals) where it refers to all brains analyzed histologically.