KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Goat anti GABRB3	Life Technologies	PA5–19060
Mouse anti GAD67	Fisher Scientific	MAB5406
Rabbit anti HCN1	Alomone Labs	APC-056
Alexa 647-conjugated IB4	Life Technologies	I16520–100
Rabbit anti MeCP2	Michael Greenberg	n/a
Goat anti PARVALBUMIN	Swant	PVG-213
Rabbit anti PARVALBUMIN	Swant	PV-27
Rabbit anti dsRED	Clontech	632496
Mouse anti Shank3	Abcam	Ab193307
Guinea pig anti vGLUT 1	Millipore	AB5905
Bacterial and Virus Strains
AAV2.9 hSyn-FLEX	Addgene	#84481
Biological Samples
Chemicals, Peptides, and Recombinant Proteins
Dexamethasone	Henry Schein	Cat. # 2459
Isoguvacine	Sigma Aldrich	Cat. #G002
Isoflurane (Isothesia)	Henry Schein	Cat. # 029405
Midazolam	Henry Schein	Cat. # 054788
Nipecotic Acid	Sigma Aldrich	Cat. # 211672
Polyinosinic: polycytidylic acid	Millipore	Cat. # 528906
T amoxifen	Toronto Research Chemicals	Cat. # 10540-29-1
Urethane	Sigma Aldrich	Cat. # U2500
Critical Commercial Assays
IonFlux HTTM Automated Patch Clamp System	Eurofins	n/a
In-Fusion® HD Cloning Plus Kit	Takara	638911
Experimental Models: Organisms/Strains
AdvillinCre	Fan Wang	Hasegawa et al., 2007
16p11.2df null	Jackson Laboratory	013128
AdvillinCreERT2	John Wood	Lau et al., 2011
Cdx2Cre	Eric Fearon	Akyol et al., 2008
Cntnap2 null	Jackson Laboratory	028635
Fmr1 null	Jackson Laboratory	003025
Gabrb3floxed	Jackson Laboratory	008310
Mecp2floxed	Jackson Laboratory	006847
Mecp2R306C	Michael Greenberg	Lyst et al., 2013
Mecp2STOP	Jackson Laboratory	006849
Shank3B Null	Jackson Laboratory	017688
Shank3Δex4-y null	Jackson Laboratory	017890
Shank3floxed	This paper	n/a
Shank3FX	Guoping Feng	Mei et al., 2016
Oligonucleotides
Primers for mouse genotyping (see Supplemental Table S8)	This paper	n/a
Recombinant DNA
AAV.hSYN.FLEx.GABRB3.t2A.mCHERRY	This paper	n/a
Software and Algorithms
ImageJ	Schneider et al., 2012	https://imagej.nih.gov/ij/
JRClust	Jun et al., 2017	https://github.com/JaneliaSciComp/JRCLUST
Other