Table 5.

Sensitivity, specificity, PPV, NPV of each reagent (former and new thresholds), 31.3% prevalence.

Assay/system	Sensitivity (%) [95% CI]	Specificity (%) [95% CI]	PPV (%)	NPV (%)
Elecsys/Cobas 8000
Positive ≥ 1.00	100 [100–100]	85.7 [82.0–89.3]	76.1	100
Positive ≥ 6.70	100 [100–100]	93.4 [90.8–96.0]	87.3	100
Architect/i2000
Positive ≥ 1.60	43.9 [38.7–49.1]	100 [100–100]	100	79.6
Positive ≥ 0.30	97.6 [95.9–99.2]	85.3 [81.6–89.0]	75.1	98.7
Platelia/Evolis
Positive ≥ 6.00	36.6 [31.6–41.6]	100 [100–100]	100	77.6
Positive ≥ 1.02	93.9 [91.4–96.4]	89.0 [85.7–92.2]	79.5	97.0

PPV, positive predictive value; NPV, negative predictive value.