Table 1. Rab11 expression in colon cancer tissues of patients grouped by various clinical parameters.

	Number of tissues (70 total)	Number of tissues with lower Rab11	Median Rab11 T/N	P value against normal
Stage
I	15	9 (60%)	0.637	0.0459
II	25	20 (80%)	0.455	0.0225
III	26	19 (73%)	0.518	0.0239
IV	4	3 (75%)	0.375	0.0346
N0M0, N0Mx	41	30 (73%)	0.489	0.0237
N1M0, N2M0	12	8 (67%)	0.591	0.148
N1M1, N2M1	4	3 (75%)	0.375	0.0346
N1Mx, N2Mxa	13	10 (77%)	0.456	0.00563a
T1	6	3 (50%)	0.615	0.247
T2	11	8 (73%)	0.626	0.016
T3a	37	31 (84%)	0.455	0.01a
T4	16	9 (56%)	0.616	0.108
N0	41	30 (73%)	0.489	0.024
N1	15	11 (73%)	0.456	0.025
N2	14	10 (71%)	0.554	0.023
M0	34	25 (74%)	0.562	0.055
M1	4	3 (75%)	0.375	0.035
Mxa	32	23 (72%)	0.438	0.009a
Age
<50	12	6 (50%)	0.647	0.129
50–70	29	21 (72%)	0.492	0.0276
>70a	29	24 (83%)	0.455	0.00914a
Sex
F	45	33 (73%)	0.462	0.0164
M	25	18 (72%)	0.498	0.0294

The clinical information of the patients is listed in an excel file https://figshare.com/s/7ec190b0f62a930ea7dc. The relative expression level in tumor tissues was calculated as fractions over that of average normal samples (T/N) as described in Materials and Methods and listed in the excel file https://figshare.com/s/7ec190b0f62a930ea7dc. The 70 samples were then grouped by various clinical information and their median expression was calculated as shown. The top part of the table is grouped by tumor stage I–IV, or NM designation represents Node and Metastasis. Mx is not known, or grouped by tumor stage by TNM pathology designation, and presented as T1–T4, N0–N2, and M0–Mx. The other table entries are grouped by the age of patient at time of diagnosis and by sex.

^aThe subgroup with the lowest P value and significant reduction of Rab11 protein level.