Table 1.

Summary of the results for the time (in sec) spent in each zone of the arena and number of interactions with the objects during the 300-second testing period. Different superscript letters represent significant differences (P < 0.05) between treatment groups from t-tests at that age.

		8 wks	28 wks				46 wks
		All animals n = 80	Control n = 42	GnRHa n = 39	GnRHa + T n = 23	All animals n = 104	Control n = 48	GnRHa n = 43	GnRHa + T n = 21	All Animals n = 102
Zone times (sec)
Neutral		129.4 ± 6.1	171.0 ± 5.1	157.1 ± 5.4	166.3 ± 6.2	164.8 ± 3.2	132.2 ± 6.0	132.5 ± 6.3	145.0 ± 7.5	134.7 ± 3.8
Entrance		70.5 ± 4.5	71.7ab ± 5.5	79.0a ± 5.7	58.9b ± 7.9	71.5 ± 3.6	107.4a ± 6.3	105.4ab ± 7.6	83.3b ± 8.8	102.1 ± 4.4
Both objects		100.1 ± 6.1	57.3a ± 3.5	64.9ab ± 4.2	74.0b ± 5.3	63.8 ± 2.5	60.4 ± 4.2	62.0 ± 4.2	71.7σ ± 4.8	63.1 ± 2.6
Familiar object		58.4 ± 5.1	31.1 ± 2.4	33.6 ± 3.0	40.0 ± 4.2	34.0 ± 1.8	28.2a ± 2.4	30.3a ± 2.5	43.1b ± 4.4	31.8 ± 1.7
	Inner	26.6 ± 2.9	17.4 ± 1.9	18.0 ± 2.1	24.6 ± 3.2	19.2 ± 1.3	13.5a ± 1.8	12.4a ± 1.4	18.6b ± 2.6	14.0 ± 1.1
	Outer	31.8 ± 2.7	13.7 ± 1.3	15.6 ± 1.6	15.4 ± 1.7	14.8 ± 0.9	14.7a ± 1.1	17.9a ± 1.6	24.5b ± 2.7	17.8 ± 1.0
Novel object		41.7 ± 3.4	26.2 ± 2.1	31.3 ± 3.5	34.0σ ± 3.1	29.8 ± 1.7	32.2 ± 2.9	31.8 ± 2.5	28.6 ± 3.3	31.4 ± 1.7
	Inner	18.2 ± 1.8	15.6 ± 1.7	19.4 ± 2.7	18.8 ± 2.2	17.7 ± 1.3	16.5 ± 2.2	15.5 ± 1.5	15.1 ± 2.3	15.8 ± 1.2
	Outer	23.5 ± 2.2	10.6a ± 1.0	11.8a ± 1.6	15.2b ± 1.7	12.1 ± 0.8	15.8 ± 1.3	16.3 ± 1.6	13.5 ± 1.7	15.5 ± 0.9
Interactions (no.)		6.5 ± 0.4	5.2b ± 0.3	5.3ab ± 0.4	6.4a,† ± 0.5	5.5 ± 0.2	5.0 ± 0.3	5.2 ± 0.4	6.1σ ± 0.6	5.3 ± 0.2
Familiar		3.6 ± 0.3	2.6ab ± 0.2	2.3b ± 0.3	3.3a,σ ± 0.4	2.8 ± 0.2	2.3a ± 0.2	2.5ab,† ± 0.2	3.4b ± 0.4	2.7 ± 0.1
Novel		2.9 ± 0.2	2.6 ± 0.2	2.9 ± 0.3	3.1 ± 0.4	2.6 ± 0.2	2.7 ± 0.2	2.7 ± 0.2	2.7 ± 0.4	2.6 ± 0.2

^σControl vs GnRHa + T P = 0.05-0.1.

^†GnRHa vs GnRHa + T P = 0.05-0.1.