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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Biomaterials. 2019 Jul 15;218:119365. doi: 10.1016/j.biomaterials.2019.119365

Fig. 1. Stability of MOF nanoparticles in different buffers.

Fig. 1.

(A), (D), and (G) are TEM images of ZrMOF, MIL-101 (Fe), and ZIF-8 nanoparticles in DMF. (B) TEM image of ZrMOF in 1X PBS for 1 hour. (C) TEM of ZrMOF-PAC in 1X PBS for 20 h. (E) TEM image of MIL-101 (Fe) in 1X PBS for 15 h. (F) TEM image of MIL-101 (Fe) in 1X PBS for 15 h. (H) TEM image of ZIF-8-PEG in sodium acetate buffer (pH = 5.5) for 1 h. (I) TEM image of ZIF-8-PEG in sodium acetate buffer (pH = 5.5) for 3 h. (ZIF-8 nanoparticles without polymer protection were dissolved completely and immediately when added to sodium acetate buffer (pH = 5.5)). Inset picture in (B) is the centrifugation result of ZrMOF in 1X PBS for 1 h. Inset picture in (C) is the centrifugation result of ZrMOF-PAC in 1x PBS for 1 h.