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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Prostate. 2019 Aug 2;79(14):1589–1596. doi: 10.1002/pros.23882

Table II.

Performance of twenty-three gene transcripts for classifying metastatic-lethal vs. non-recurrent prostate cancer in the Mayo Clinic training dataset

Transcript ID Gene Mean expression no recurrence Mean expression metastatic-lethal Difference in mean expression P-value t-test AUC P-value AUC pAUC P-value pAUC
ILMN_1748538 ALDH1A2 0.23 0.20 −0.03 3 × 10−4 0.61 < 1.00 × 10−6 0.0023
ILMN_1786125 CCNA2 0.05 0.06 0.01 0.464 0.49 0.950 0.0014 0.496
ILMN_1716279 CENPE −0.10 −0.08 0.02 0.014 0.56 0.036 0.0025 0.091
ILMN_1694584 CLTCL1 −0.04 −0.05 −0.01 0.097 0.55 0.090 0.0042 0.005
ILMN_1673843 CST2 0.23 0.30 0.07 2 × 10−4 0.61 1 × 10−3 0.0031 0.041
ILMN_1708107 DPT 0.26 0.19 −0.07 1 × 10−4 0.62 < 1.00 × 10−6 0.0041 4 × 10−3
ILMN_1700541 FBLN1 0.21 0.15 −0.06 < 1.00 × 10−6 0.63 < 1.00 × 10−6 0.0039 4 × 10−3
ILMN_1756358 FBXO36 0.03 0.02 −0.01 0.273 0.52 0.586 0.0014 0.535
ILMN_2406084 ITGA11 0.07 0.07 0.00 0.770 0.51 0.652 0.0017 0.339
ILMN_1702738 KLC3 −0.02 −0.04 −0.02 0.341 0.52 0.485 0.0008 0.865
ILMN_1661895 PI15 0.51 0.49 −0.03 0.491 0.54 0.141 0.0039 4 × 10−3
ILMN_1734810 PJA1 0.36 0.36 0.00 0.781 0.51 0.769 0.0008 0.846
ILMN_1737025 PLCL2 0.08 0.05 −0.03 5.3 × 10−3 0.58 4 × 10−3 0.0026 0.076
ILMN_1794490 PNMAL1 −0.03 −0.04 −0.01 0.301 0.53 0.368 0.0025 0.114
ILMN_1739393 SELE 0.16 0.13 −0.03 1.3 × 10−3 0.60 1 × 10−3 0.0033 0.032
ILMN_1730295 SIGLEC8 −0.04 −0.05 −0.01 0.550 0.50 0.813 0.0002 0.988
ILMN_2086105 SPRY4 0.20 0.24 0.04 4.2 × 10−3 0.57 0.013 0.0038 0.012
ILMN_1788895 SRD5A2 −0.12 −0.17 −0.05 1 × 10−4 0.62 < 1.00 × 10−6 0.0032 0.029
ILMN_1704154 TNFRSF19 0.25 0.19 −0.07 < 1.00 × 10−6 0.64 < 1.00 × 10−6 0.0026 0.103
ILMN_2089875 TNFSF4 0.04 0.05 0.01 0.487 0.52 0.411 0.0027 0.081
ILMN_1796949 TPX2 0.18 0.24 0.06 < 1.00 × 10−6 0.64 < 1.00 × 10−6 0.0057 < 1.00 × 10−6
ILMN_1748124 TSC22D3 0.09 0.08 0.00 0.648 0.50 0.784 0.0018 0.285
ILMN_1656192 ZNF704 0.30 0.36 0.06 < 1.00 × 10−6 0.61 < 1.00 × 10−6 0.0053 < 1.00 × 10−6

Validated transcripts (n = 13) with the same direction of expression difference as in the original datasets (Rubicz et al., 2017); gene transcripts with significant p-values are shown in boldface.