Table 4. AR-Pred performance compared with other active site prediction methods.
The percentage of proteins for which AR-Pred predicts the same or a larger number of true positive active site residues relative to the other methods is tabulated. The calculations are reported for different percent thresholds that consider the top 10, 20, 30, 40 and 50 percent of predictions.
| Threshold Percent╲Method | Concavity | AADS | POOL | FOD |
|---|---|---|---|---|
| 10 | 57.9 | 89.5 | 61.1 | 84.2 |
| 20 | 36.8 | 73.7 | 72.2 | 89.5 |
| 30 | 57.9 | 79.0 | 77.8 | 89.5 |
| 40 | 63.2 | 79.0 | 61.1 | 63.2 |
| 50 | 68.4 | 84.2 | 66.7 | 79.0 |
| Median | 57.9 | 79.0 | 66.7 | 84.2 |