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. 2019 Sep 2;20:549. doi: 10.1186/s13063-019-3601-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Standard protocol items: recommendation for interventional trials (SPIRIT) schedule of enrolment, interventions and assessments. ^aBlood and urine tests for HbA1c, renal panel, calculated estimated glomerular filtration rate (eGFR), fasting lipid profile (total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL)) and urine albumin:creatinine ratio. ^bDiabetes Distress Screen Scale (DDS17) and Medication Adherence Report Scale-5 (MARS-5) questionnaires. m, month; MSW, medical social worker; DNE, diabetes nurse educator; FU, follow up; IMT, intima-media thickness