Table 3.
Mice | Hairless | Nude | SCID Hairless | Nude R/J | |
---|---|---|---|---|---|
Strain | BALB/c | BALB/c | CB17.Cg/ICR | BALB/c | |
Gene abnormality | Hairless | Foxn1 | Hairless, SCID |
Foxn1, Rag-2, Jak3 | |
Immune system | T cells | + | − | − | − |
B cells | + | + | − | − | |
NK cells | + | + | + | − | |
Hair coat | None | None | None | None |
+: intact certain immune cells, −: lack of certain cells. Foxn1 = forkhead box N1.