Figure 1.

Cartoon and solvent drawing of the predicted PPRV H-SLAM complex. The complexes of the H protein’s six-bladed β-propeller head domain and the receptor SLAM V-like were built, in which β4–β6 of the head domain and the typical β-sandwich structure of the V domain were interacting surfaces. (A and B) show the analysis of the hydrophobicity of PPRV H and sheep SLAM, indicating that there was a strong hydrophobic groove between β4–β6 on the H head domain, and the surface on the sheep SLAM had stronger hydrophobicity. (C) A structure comparison revealed that the PPRV H-sheep SLAM and PPRV H-human SLAM complexes are very similar. (D) Interaction patterns between PPRV H and human SLAM.