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Reasons for slow adoption of PR PLTs in the United States
| Current safety of the volunteer blood supply |
| Success of surveillance and screening in dealing with emerging pathogens |
| Inability of current technologies to inactivate all agents (small nonencapsulated viruses, spores, high titers of virus, and prions) |
| Efficacy concerns |
| No single method to treat all components |
| Regulatory requirements |
| Cost |
