Fig. 1.

The time course of the expression of 4-hydroxy-2-nonenal in left ventricle at 0, 3, 7, 10 and 14 days after surgery. Representative immunohistochemical staining showing 4-hydroxy-2-nonenal in left ventricle obtained from fistula created rat (A). All figures are depicted at 400×magnification. The scale represents 50 μm. Semi-quantification of 4-hydroxy-2-nonenal expression in left ventricle (B). Each value represents the mean ± S.E.M. of number of animals in parentheses. **P < 0.01, *P < 0.05, compared with day 0. 4-HNE, 4-hydroxy-2-nonenal.