Table 3. SIRs by estimated duration of use and 95% CIs of gastric cancer in those exposed to PPIs.

SIR - standardized incidence ratio, CI - confidence interval

Note: reprinted from Brusselaers N, Wahlin K, Engstrand L, et al. [17]

Duration	Cases (n)/total	SIR (95%CI)
<1.0 year	1,552	12.82 (12.19-13.47)
1.0-2.9 years	2,193	2.19 (1.98-2.42)
3.0-4.9 years	1,098	1.10 (0.91-1.31)
≥5.0 years	153	0.61 (0.52-0.72)