Figure 4.

Rice Rat Primary Cultures Secrete Fluid in Response to Carbachol

(A–C) Apical fluid secretion in response to 100 μM basolateral carbachol in mouse (A), pig (B), and rice rat (C) airway cultures.

(D) Fluid secretion responses normalized to baseline values and expressed as a percent for each species. For all panels, n = 4 cultures from mice (2 female cultures and 2 male cultures representing 6 female and 6 male subjects); n = 6 cultures from the rice rat (3 female cultures and 3 male cultures representing 6 female and 6 male subjects); n = 6 porcine cultures (3 female and 3 male representing 3 individual female and 3 individual male subjects). ∗p < 0.05 compared with baseline. All data are shown as mean ± SEM.