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International Journal of Chronic Obstructive Pulmonary Disease logoLink to International Journal of Chronic Obstructive Pulmonary Disease
. 2019 Sep 3;14:2061–2064. doi: 10.2147/COPD.S229124

Effect of tiotropium/olodaterol on sedentary and active time in patients with COPD: post hoc analysis of the VESUTO® study [Erratum]

PMCID: PMC6733181  PMID: 31564853

Minakata Y, Motegi T, Ueki J, et al. Int J Chron Obstruct Pulmon Dis. 2019;14:1789–1801.

During the publication process there was an operator error where the supplementary materials, mentioned on pages 1790 and 1793, were omitted from the manuscript. The supplementary materials are listed below:

We apologize for this oversight.

Supplementary materials

Figure S1

The effect of tiotropium/olodaterol combination therapy versus tiotropium monotherapy on time spent in 1.0–1.5 METs (A), ≥2.0 METs (B), and ≥3.0 METs (C) activity levels (percent change from baseline) by subgroup.

Abbreviations: BMI, body mass index; CI, confidence interval; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; GOLD, global initiative for chronic obstructive pulmonary disease; IC, inspiratory capacity; METs, metabolic equivalents; mMRC, modified Medical Research Council; SGRQ, St George’s Respiratory Questionnaire; Tio, tiotropium; T+O, tiotropium/olodaterol.

graphic file with name COPD_A_229124_O_SF0001g.jpg

Figure S2

The relationship between improvements in lung function and duration of 1.0–1.5 METs (A), ≥2.0 METs (B), and ≥3.0 METs (C) activity levels (percent change from baseline).

Abbreviations: CI, confidence interval; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; IC, inspiratory capacity; METs, metabolic equivalents; Tio, tiotropium; T+O, tiotropium/olodaterol.

graphic file with name COPD_A_229124_O_SF0002g.jpg

Figure S3

Improvement in physical activity in patients with and without FEV1 response. FEV1 ≥100 mL was defined as the minimal clinically important difference (between tiotropium/olodaterol combination therapy and tiotropium monotherapy).

Abbreviations: FEV1, forced expiratory volume in 1 s; METs, metabolic equivalents.

graphic file with name COPD_A_229124_O_SF0003g.jpg

Table S1.

Institutional review board list

Institutional Review Board (location)
Hokkaido University Hospital (Sapporo, Hokkaido, Japan)
Hoshikuma Hihuka Allergy Clinic (Fukuoka, Fukuoka, Japan)
Iwate Medical University Hospital (Morioka, Iwate, Japan)
Japan Community Health care Organization Hokkaido Hospital (Sapporo, Hokkaido, Japan)
Japan Organization of Occupational Health and Safety Tohoku Rosai Hospital (Sendai, Miyagi, Japan)
Juntendo University Hospital (Bunkyo-ku, Tokyo, Japan)
Kagoshima University Hospital And Dental Hospital (Kagoshima, Kagoshima, Japan)
Kindai University Hospital (Osakasayama, Osaka, Japan)
Kishiwada City Hospital (Kishiwada, Osaka, Japan)
KKR Sapporo Medical Center (Sapporo, Hokkaido, Japan)
Kobe City Hospital Organization Kobe City Medical Center West Hospital (Kobe, Hyogo, Japan)
Kobe City Medical Center General Hospital (Kobe, Hyogo, Japan)
Koyasu Neurosurgical Clinic (Yokohama, Kanagawa, Japan)
Kurume University Hospital (Kurume, Fukuoka, Japan)
Kyoto University Hospital (Kyoto, Kyoto, Japan)
K-you Health Care Co. Kirigaoka Tsuda Hospital (Kitakyushu, Fukuoka, Japan)
Matsusaka City Hospital (Matsusaka, Mie, Japan)
National Center for Geriatrics and Gerontology (Obu, Aichi, Japan)
NHO Himeji Medical Center (Himeji, Hyogo, Japan)
NHO Ibarakihigashi National Hospital (Naka-gun, Ibaraki, Japan)
NHO Tenryu Hospital (Hamamatsu, Shizuoka, Japan)
NHO Toneyama National Hospital (Toyonaka, Osaka, Japan)
NHO Wakayama Hospital (Hidaka-gun, Wakayama, Japan)
Nihon Kokan Hospital (Kawasaki, Kanagawa, Japan)
Nihon Medical School (Bunkyo-ku, Tokyo, Japan)
Nihon University Itabashi Hospital (Itabashi-ku, Tokyo, Japan)
Nihonbashi Sakura Clinic (Chuo-ku, Tokyo, Japan)
Nishi Fukuoka Hospital (Fukuoka, Fukuoka, Japan)
Osaka City University Hospital (Osaka, Osaka, Japan)
Rakuwakai Otowa Hospital (Kyoto, Kyoto, Japan)
Sakaide City Hospital (Sakaide, Kagawa, Japan)
Shimane University Hospital (Izumo, Shimane, Japan)
Shinagawa East One Medical Clinic (Minato-ku, Tokyo, Japan)
Showa University Fujigaoka Hospital (Yokohama, Kanagawa, Japan)
Showa University Hospital (Shinagawa-ku, Tokyo, Japan)
Teine Keijinkai Clinic (Sapporo, Hokkaido, Japan)
Tohoku University Hospital (Sendai, Miyagi, Japan)
Tokyo-Eki Center-building Clinic (Chuo-ku, Tokyo, Japan)
Tokyo Medical University Hachioji Medical Center (Hachioji, Tokyo, Japan)
Tosei General Hospital (Seto, Aichi, Japan)
Tokushukai Group Institutional review Board (Chiyoda-ku, Tokyo, Japan)

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

Figure S1

The effect of tiotropium/olodaterol combination therapy versus tiotropium monotherapy on time spent in 1.0–1.5 METs (A), ≥2.0 METs (B), and ≥3.0 METs (C) activity levels (percent change from baseline) by subgroup.

Abbreviations: BMI, body mass index; CI, confidence interval; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; GOLD, global initiative for chronic obstructive pulmonary disease; IC, inspiratory capacity; METs, metabolic equivalents; mMRC, modified Medical Research Council; SGRQ, St George’s Respiratory Questionnaire; Tio, tiotropium; T+O, tiotropium/olodaterol.

graphic file with name COPD_A_229124_O_SF0001g.jpg

Figure S2

The relationship between improvements in lung function and duration of 1.0–1.5 METs (A), ≥2.0 METs (B), and ≥3.0 METs (C) activity levels (percent change from baseline).

Abbreviations: CI, confidence interval; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; IC, inspiratory capacity; METs, metabolic equivalents; Tio, tiotropium; T+O, tiotropium/olodaterol.

graphic file with name COPD_A_229124_O_SF0002g.jpg

Figure S3

Improvement in physical activity in patients with and without FEV1 response. FEV1 ≥100 mL was defined as the minimal clinically important difference (between tiotropium/olodaterol combination therapy and tiotropium monotherapy).

Abbreviations: FEV1, forced expiratory volume in 1 s; METs, metabolic equivalents.

graphic file with name COPD_A_229124_O_SF0003g.jpg


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