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suPAR serum levels are elevated in PDAC patients. (A) PDAC patients display significantly elevated serum suPAR levels compared to healthy control samples and patients with pancreatic intraepithelial neoplasia (PanIN) lesions. (B) Baseline suPAR levels show an AUC value of 0.940 regarding the discrimination of PDAC patients and healthy controls. (C) The combination of circulating suPAR and CA19-9 levels further improved the diagnostic potential.
