Fig. 2.

Graphic illustration of lives that could be saved annually through the development of innovative vaccines and improved global availability of vaccines. Bar chart illustrates the mortality of global disease burden due to 12 diseases that could be prevented through innovations in vaccines against TB, HIV, Malaria, Shigella, Typhoid, RSV, GBS, ETEC, Norovirus and Dengue vaccines to save 3.3 million lives. Higher availability of Pneumococcal and new generation Rotavirus vaccines could save additional lives, bringing the total estimated lives saved to 3.8 million annually. Bar sizes are only subjectively estimated, indicative of the number of deaths reported in 132 countries. Coloured areas divide the vaccines into three main categories: green = most needed vaccines; orange = not yet available vaccines; grey = vaccines available at limited supply. Improving vaccines manufacturing, supply capacity and availability would save 3.8 million lives. All rates reported here are age-standardised and derived from WHO and Lancet disease burden estimates, represented in a simple illustrative manner, as to data published in 2017 (at the time of the meeting). The purpose of GBD 2017 is to serve as a global public good, freely available for policy makers and the public seeking to improve human health. A detailed description of Data and statistical modelling tools are available at https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32203-7/fulltext. (*) Note that new typhoid vaccines became globally available after 2018. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)