Table 1.
Clinical and biochemical characteristics of obese patients with mild to moderate fibrosis (F0–2) compared to patients with advanced fibrosis (F3–4) on liver biopsy.
| Characteristics | F score |
p-Value | |
|---|---|---|---|
| 0–2 | 3–4 | ||
| Gender (m/f) | f = 21, m = 1 | f = 6, m = 6 | |
| Age (years) | 45 ± 3 | 49 ± 3 | 0.32 |
| BMI (kg/m2) | 48.8 ± 1.7 | 48.0 ± 2.3 | 0.788 |
| T2DM (%) | 18 (4/22) | 92 (11/12)*** | <0.001 |
| AST (IU/L) | 22 ± 1 | 32 ± 5* | 0.016 |
| ALT (IU/L) | 29 ± 2 | 37 ± 7 | 0.167 |
| Platelets (x109/L) | 269 ± 11 | 239 ± 23 | 0.198 |
| AST/ALT ratio | 0.85 ± 0.05 | 0.92 ± 0.11 | 0.569 |
| FIB-4 score | 0.76 ± 0.08 | 1.55 ± 0.36** | 0.007 |
| Ferritin (ug/L) | 102 ± 13 | 120 ± 20 | 0.448 |
| HbA1c (%) | 5.5 ± 0.1 | 6.4 ± 0.4** | 0.004 |
| Total Chol (mmol/L) | 4.6 ± 0.3 | 4.0 ± 0.3 | 0.16 |
| HDL (mmol/L) | 1.0 ± 0.05 | 0.8 ± 0.03** | 0.008 |
| LDL (mmol/L) | 2.8 ± 0.2 | 2.3 ± 0.3 | 0.178 |
| Chol/HDL ratio | 4.6 ± 0.2 | 4.8 ± 0.3 | 0.597 |