Skip to main content
The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2019 Sep 13;294(37):13830. doi: 10.1074/jbc.W119.010660

Withdrawal: Thromboxane A2 receptor activates a Rho-associated kinase/LKB1/PTEN pathway to attenuate endothelium insulin signaling.

Ping Song, Miao Zhang, Shaungxi Wang, Jian Xu, Hyoung Chul Choi, Ming-Hui Zou
PMCID: PMC6746448  PMID: 31519759

VOLUME 284 (2009) PAGES 17120–17128

This article has been withdrawn by the authors. The Journal raised questions that the Akt immunoblot in Fig. 2A was reused in Fig. 5B; lanes 1, 2, and 4 of the actin immunoblot in Fig. 4A are the same; the LKB1 immunoblot in Fig. 7B was reused in Fig. 7D; and lane 2 of the tubulin immunoblot in Fig. 9A was reused in lane 1 for Fig. 9C. The authors were able to locate some of the original data and were able to locate some repeated experiments performed at the time of the original work, which the authors state support the conclusions of the paper. The authors offered to publish amended figures based upon that data and, alternatively, offered to repeat the experiments. However, the Journal declined both offers, a decision with which the authors disagree. Further, the authors state that the results of this paper are confirmed by the results of complementary experiments presented in the article and that some of the principal observations of this article were further confirmed in publications from other laboratories (Soliman, H. et al. (2015) Am. J. Physiol. Heart Circ. Physiol. 309, H70–H81; Lee, S-H. et al. (2014) Am. J. Physiol. Endocrinol. Metab. 306, E332–E343). The authors stand by the conclusions of the paper.


Articles from The Journal of Biological Chemistry are provided here courtesy of American Society for Biochemistry and Molecular Biology

RESOURCES