Table 3. Univariate and multivariate cox regression analyses for OS and DFS in ccRCC patients.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	p-value	HR (95% CI)	p-value
Overall survival
Age	1.03(1.01–1.04)	0.00000229	1.03(1.02–1.05)	0.00000107
Gender	0.93(0.67–1.28)	0.662936583
Histological grade	2.29(1.85–2.83)	1.94E−14	1.40(1.10–1.79)	0.005937457
Pathological stage	1.88(1.64–2.16)	4.67E−20	1.60(1.03–2.48)	0.034897661
T stage	1.94(1.63–2.29)	1.5E−14	0.87(0.58–1.31)	0.528085268
M stage	4.28(3.10–5.90)	7.45E−19	1.45(0.74–2.84)	0.27403342
AURKB	1.13(1.09–1.16)	2.42E−13	1.09(1.05–1.14)	0.00000276
Disease free survival
Age	1.00(0.99–1.02)	0.20947696
Gender	1.35(0.91–2.01)	0.132201537
Histological grade	2.97(2.29–3.83)	8.11792E−17	1.73(1.33–2.25)	4.49123E-05
Pathological stage	2.65(2.22–3.17)	5.19396E−27	2.33(1.30–4.18)	0.004223284
T stage	2.5(2.02–3.08)	1.92212E−17	0.79(0.46–1.33)	0.384923805
M stage	8.52(5.87–12.37)	1.95879E−29	1.47(0.63–3.43)	0.361781114
AURKB	1.13(1.09–1.18)	3.0124E−09	1.07(1.01–1.13)	0.019973352