Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 15;38(12):2092–2107. doi: 10.1038/s41388-018-0562-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — Dll1 promotes cancer stem cell (CSC) population in luminal/non-TNBC tumors. a FACS data show reduced in vitro CSC population (CD24⁻CD44⁺ population) in WTB Dll1-KDs (KD2 and KD4) cells compared to control cells. b FACS data show reduced in vivo CSCs population in primary tumors derived from injection of WTB Dll1-KDs (KD2 and KD4) cells compared to control tumors using CD24/CD44 markers. c Bar graph shows percentage of CSC population in WTB Dll1-KD (KD2 and KD4) tumor cells compared to control tumor cells. d, f FACS data show reduced in vivo CSC population (CD24⁻CD44⁺ population) in primary tumors derived from injection of MCF7 DLL1-KD (KD1 and KD2) cells and DLL1 overexpression (DLL1-OE) cells compared to their respective control tumors. e, g Bar graphs show the quantification of CSC population (CD24⁻CD44⁺ population) in DLL1-KDs (KD1 and KD2) and DLL1-OE compared to their respective controls. Scatter plots represent number of animals as dots. Mann−Whitney U test was used to compute p values. Data are presented as the mean ± SEM. *p < 0.05 and **p < 0.01