Table 1.
86 differentially expressed genes (DEGs) between the IRO and ISO subjects.
| Gene symbol | LogFC | P.Value | Adj.P.Val | Discription |
|---|---|---|---|---|
| SELE | 1.879096 | 0.003469 | 0.010998 | Selectin E |
| FOSB | 1.862047 | 0.005321 | 0.015295 | FosB Proto-Oncogene, AP-1 Transcription Factor Subunit |
| CH25H | 1.861392 | 0.000147 | 0.001037 | Cholesterol 25-Hydroxylase |
| CCL3L3 | 1.637939 | 0.000161 | 0.0011 | C-C Motif Chemokine Ligand 3 Like 3 |
| IL6 | 1.593556 | 0.003843 | 0.011902 | Interleukin 6 |
| CCL2 | 1.509892 | 0.000415 | 0.002205 | C-C Motif Chemokine Ligand 2 |
| CXCL8 | 1.476708 | 2.80E-05 | 0.000332 | C-X-C Motif Chemokine Ligand 8 |
| MMP9 | 1.434427 | 2.67E-05 | 0.000321 | Matrix Metallopeptidase 9 |
| CCL8 | 1.233571 | 0.000148 | 0.001041 | C-C Motif Chemokine Ligand 8 |
| BCL2A1 | 1.207528 | 1.96E-05 | 0.000264 | BCL2 Related Protein A1 |
| CCL4 | 1.189727 | 0.000822 | 0.003646 | C-C Motif Chemokine Ligand 4 |
| SLC2A3 | 1.059321 | 0.000437 | 0.002277 | Solute Carrier Family 2 Member 3 |
| CXCL10 | 1.040682 | 0.001537 | 0.005848 | C-X-C Motif Chemokine Ligand 10 |
| PTGS2 | 1.014023 | 0.003974 | 0.012219 | Prostaglandin-Endoperoxide Synthase 2 |
| EZR | −1.00561 | 0.001522 | 0.005807 | Ezrin |
| FGF10 | −1.00813 | 1.79E-05 | 0.000247 | Fibroblast Growth Factor 10 |
| LOC730101 | −1.01143 | 7.46E-08 | 1.11E-05 | Uncharacterized LOC730101 |
| PDZK1IP1 | −1.01724 | 1.80E-05 | 0.000248 | PDZK1 Interacting Protein 1 |
| GPT2 | −1.02266 | 1.21E-06 | 4.58E-05 | Glutamic–Pyruvic Transaminase 2 |
| CCDC182 | −1.02634 | 1.03E-08 | 3.54E-06 | Coiled-Coil Domain Containing 182 |
| LOC105379499 | −1.02832 | 0.000278 | 0.001641 | Uncharacterized LOC105379499 |
| GPM6A | −1.03013 | 1.12E-06 | 4.42E-05 | Glycoprotein M6A |
| RARRES1 | −1.03198 | 0.004503 | 0.013463 | Retinoic Acid Receptor Responder 1 |
| RBMS3-AS3 | −1.03424 | 1.97E-08 | 5.06E-06 | RBMS3 Antisense RNA 3 |
| DAPK1 | −1.03754 | 5.38E-07 | 2.94E-05 | Death Associated Protein Kinase 1 |
| DSC3 | −1.03987 | 1.58E-05 | 0.000227 | Desmocollin 3 |
| LOC286191 | −1.03992 | 1.81E-05 | 0.000249 | Uncharacterized LOC286191 |
| MGC24103 | −1.05252 | 6.67E-06 | 0.00013 | uncharacterized MGC24103 |
| OGN | −1.06052 | 0.000837 | 0.003696 | Osteoglycin |
| PEG3-AS1 | −1.06077 | 8.06E-07 | 3.62E-05 | PEG3 Antisense RNA 1 |
| BCO2 | −1.07343 | 4.01E-05 | 0.000425 | Beta-Carotene Oxygenase 2 |
| WNT5A | −1.07968 | 5.03E-05 | 0.000497 | Wnt Family Member 5A |
| PTPN13 | −1.08707 | 3.56E-05 | 0.000392 | Protein Tyrosine Phosphatase Non-Receptor Type 13 |
| ADGRD1 | −1.09049 | 0.000745 | 0.003394 | Adhesion G Protein-Coupled Receptor D1 |
| MUC16 | −1.09179 | 0.000337 | 0.001897 | Mucin 16, Cell Surface Associated |
| COL8A1 | −1.0999 | 2.43E-05 | 0.000303 | Collagen Type VIII Alpha 1 Chain |
| SGO2 | −1.10134 | 0.002526 | 0.008593 | Shugoshin 2 |
| REEP1 | −1.10205 | 0.000224 | 0.0014 | Receptor Accessory Protein 1 |
| HAND2-AS1 | −1.11029 | 8.44E-06 | 0.000151 | HAND2 Antisense RNA 1 |
| FAM184B | −1.11123 | 5.55E-05 | 0.000529 | Family With Sequence Similarity 184 Member B |
| SERTM1 | −1.11179 | 0.006541 | 0.017993 | Serine Rich And Transmembrane Domain Containing 1 |
| HSD17B6 | −1.11252 | 0.007312 | 0.019676 | Hydroxysteroid 17-Beta Dehydrogenase 6 |
| KLK5 | −1.11374 | 8.95E-05 | 0.00073 | Kallikrein Related Peptidase 5 |
| ADAMTS3 | −1.12108 | 3.45E-06 | 8.63E-05 | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 3 |
| SLPI | −1.12146 | 0.002489 | 0.008497 | Secretory Leukocyte Peptidase Inhibitor |
| KCNK17 | −1.12528 | 1.29E-06 | 4.74E-05 | Potassium Two Pore Domain Channel Subfamily K Member 17 |
| FZD7 | −1.12933 | 2.02E-05 | 0.000269 | Frizzled Class Receptor 7 |
| SLC6A18 | −1.14746 | 1.11E-09 | 1.27E-06 | Solute Carrier Family 6 Member 18 |
| MYOC | −1.15129 | 0.000196 | 0.001269 | Myocilin |
| OSR1 | −1.18335 | 0.000381 | 0.002076 | Odd-Skipped Related Transcription Factor 1 |
| LOC107985971 | −1.18454 | 4.19E-05 | 0.000436 | Uncharacterized LOC107985971 |
| LOC101930363 | −1.18661 | 0.001718 | 0.006357 | Uncharacterized LOC101930363 |
| NNAT | −1.19253 | 0.000392 | 0.002116 | Neuronatin |
| MUM1L1 | −1.19258 | 0.000198 | 0.001281 | Mutated Melanoma-Associated Antigen 1-Like Protein 1 |
| CRISPLD1 | −1.19426 | 0.000157 | 0.001088 | Cysteine Rich Secretory Protein LCCL Domain Containing 1 |
| SLC28A3 | −1.21083 | 0.000124 | 0.000918 | Solute Carrier Family 28 Member 3 |
| PCP4 | −1.21751 | 1.73E-05 | 0.000242 | Purkinje Cell Protein 4 |
| STK26 | −1.23583 | 9.86E-05 | 0.000785 | Serine/Threonine Kinase 26 |
| LRP2 | −1.24535 | 6.50E-05 | 0.000589 | LDL Receptor Related Protein 2 |
| HCAR1 | −1.24879 | 3.40E-07 | 2.25E-05 | Hydroxycarboxylic Acid Receptor 1 |
| MSLN | −1.25677 | 0.002926 | 0.009622 | Mesothelin |
| UPK3B | −1.2569 | 0.015278 | 0.035445 | Uroplakin 3B |
| CLIC3 | −1.2602 | 0.000327 | 0.001854 | Chloride Intracellular Channel 3 |
| CCL21 | −1.27874 | 0.002635 | 0.00887 | C-C Motif Chemokine Ligand 21 |
| KCNT2 | −1.29148 | 0.000103 | 0.000807 | Potassium Sodium-Activated Channel Subfamily T Member 2 |
| SUSD5 | −1.29173 | 3.51E-05 | 0.000387 | Sushi Domain Containing 5 |
| NELL2 | −1.29529 | 1.14E-05 | 0.000184 | Neural EGFL Like 2 |
| FKBP5 | −1.31942 | 0.000426 | 0.002244 | FKBP Prolyl Isomerase 5 |
| SLC27A2 | −1.34127 | 3.38E-05 | 0.000377 | Solute Carrier Family 27 Member 2 |
| FAM110C | −1.34917 | 0.004246 | 0.012852 | Family With Sequence Similarity 110 Member C |
| TCEAL2 | −1.35659 | 5.22E-06 | 0.00011 | Transcription Elongation Factor A Like 2 |
| MGARP | −1.3571 | 0.00076 | 0.003442 | Mitochondria Localized Glutamic Acid Rich Protein |
| ANXA8L1 | −1.41631 | 0.003195 | 0.010298 | Annexin A8 Like 1 |
| WT1 | −1.46178 | 0.000737 | 0.003366 | WT1 Transcription Factor |
| DMKN | −1.48658 | 1.41E-07 | 1.46E-05 | Dermokine |
| BCHE | −1.51598 | 0.000649 | 0.003057 | Butyrylcholinesterase |
| FAM221A | −1.52345 | 3.00E-10 | 5.43E-07 | Family With Sequence Similarity 221 Member A |
| TMEM255A | −1.52749 | 0.0003 | 0.001738 | Transmembrane Protein 255A |
| MMRN1 | −1.57297 | 0.000467 | 0.002391 | Multimerin 1 |
| GPAT3 | −1.61959 | 4.73E-09 | 2.57E-06 | Glycerol-3-Phosphate Acyltransferase 3 |
| PKHD1L1 | −1.6242 | 0.001835 | 0.006696 | Polycystic Kidney And Hepatic Disease 1 (Autosomal Recessive)-Like 1 |
| AZGP1 | −1.6757 | 3.82E-11 | 4.16E-07 | Alpha-2-Glycoprotein 1, Zinc-Binding |
| FLRT3 | −1.69116 | 8.87E-05 | 0.000727 | Fibronectin Leucine Rich Transmembrane Protein 3 |
| PTPRZ1 | −1.72517 | 8.63E-09 | 3.29E-06 | Protein Tyrosine Phosphatase Receptor Type Z1 |
| ANGPTL7 | −1.87141 | 3.28E-07 | 2.22E-05 | Angiopoietin Like 7 |
| XIST | −1.88809 | 0.018291 | 0.040896 | X Inactive Specific Transcript |