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LMNA gene analysis in the pedigree.
(a). Genetic analysis of the LMNA gene of the patient and her pedigree. (b). The search for the LMNA R133L mutation in the patient’s relatives (arrow: proband). (c). Sequence conservation of R133 in vertebrate LMNA data in the Swiss-Prot database (with accession numbers) and alignments around the conserved R133 residue (red).
