Table 2.
Multivariate analysis to predict 6-week outcomes.
| Parameter | Beta Coefficient | Standard Error | Odds Ratios (95%CI) | p |
|---|---|---|---|---|
| Univariate logistic regression | ||||
| mNUTRIC score | 0.849 | 0.175 | 2.338 (1.658–3.296) | <0.001 |
| High mNUTRIC score | 3.516 | 0.770 | 33.648 (7.437–152.243) | <0.001 |
| Child–Pugh score | 1.007 | 0.200 | 2.738 (1.850–4.053) | <0.001 |
| SOFA score | 0.586 | 0.115 | 1.796 (1.434–2.250) | <0.001 |
| APACHE II | 0.176 | 0.036 | 1.192 (1.112–1.278) | <0.001 |
| MELD | 0.175 | 0.033 | 1.191 (1.116–1.272) | <0.001 |
| CRP (mg/L) | 0.017 | 0.006 | 1.017 (1.005–1.030) | 0.007 |
| Bilirubin (mg/dL) | 0.180 | 0.044 | 1.197 (1.098–1.305) | <0.001 |
| INR | 3.044 | 0.625 | 20.980 (6.157–71.481) | <0.001 |
| Serum creatinine (mg/dL) | 0.528 | 0.138 | 1.695 (1.293–2.223) | <0.001 |
| Leukocytes (×109/L) | 0.082 | 0.035 | 1.085 (1.014–1.162) | 0.0185 |
| Blood transfusion (unit) | 0.291 | 0.079 | 1.337 (1.146–1.561) | <0.001 |
| Mean arterial pressure (mmHg) | −0.096 | 0.025 | 0.908 (0.865–0.953) | <0.001 |
| Shock (%) | 2.616 | 0.648 | 13.676 (3.838–48.730) | <0.001 |
| Ascites (%) | 2.951 | 1.039 | 19.119 (2.494–146.557) | 0.005 |
| Hepatic encephalopathy (%) | 1.386 | 0.536 | 4.000 (1.398–11.446) | 0.010 |
| Bacterial infection at inclusion (%) | 2.436 | 0.524 | 11.428 (4.090–31.929) | <0.001 |
| Treatment failure (%) | 2.973 | 0.563 | 19.556 (6.488–58.947) | 0.001 |
| ICU stay (days) | 0.064 | 0.024 | 1.066 (1.017–1.117) | 0.007 |
| Multivariate logistic regression (Model 1) | ||||
| mNUTRIC score | 0.770 | 0.238 | 2.160 (1.355–3.445) | 0.001 |
| Bacterial infection at inclusion | 1.980 | 0.819 | 7.240 (1.453–36.071) | 0.016 |
| Child–Pugh score | 0.954 | 0.274 | 2.596 (1.518–4.439) | <0.001 |
| Multivariate logistic regression (Model 2) | ||||
| mNUTRIC score | 0.875 | 0.292 | 2.399 (1.353–4.256) | 0.003 |
| Bacterial infection at inclusion | 3.155 | 0.948 | 23.443 (3.659–150.178) | 0.001 |
| MELD score | 0.184 | 0.052 | 1.202 (1.086–1.330) | <0.001 |
Abbreviations: mNUTRIC, Modified Nutrition Risk in the Critically Ill; BMI, SOFA, Sequential Organ Failure Assessment; APACHE II, acute physiology and chronic health evaluation II; MELD, Model for End-Stage Liver Disease; CRP, C-reactive protein; INR, international normalized ratio; ICU, intensive care unit; CI, confidence interval.