Figure 4.

Effect of CsA and AdN on mitochondrial Ca²⁺ buffering capacity. Mitochondrial Ca²⁺ buffering capacity calculated from trend fits of [Ca²⁺]_e and [Ca²⁺]_m for DMSO-(control), CsA-, and OMN+ADP-treated mitochondria as described by Equations (2)–(4) in Materials and Methods. Buffering capacity for each treatment was calculated from three-five experiments each for [Ca²⁺]_e and [Ca²⁺]_m and averaged. Error bars represent mean ± SEM (* p < 0.01 compared with DMSO).