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. 2019 Oct 2;6(19):1970117. doi: 10.1002/advs.201970117

Nanomedicine: Biologically Targeted Photo‐Crosslinkable Nanopatch to Prevent Postsurgical Peritoneal Adhesion (Adv. Sci. 19/2019)

Yu Mi 1, Feifei Yang 1,2, Cameron Bloomquist 1,3, Youli Xia 4, Bo Sun 1, Yanfei Qi 1,5, Kyle Wagner 1, Stephanie A Montgomery 6, Tian Zhang 7, Andrew Z Wang 1
PMCID: PMC6774014

Abstract

In article number 1900809, Andrew Z. Wang and co‐workers develop a strategy to prevent postsurgical adhesion using a biologically targeted photo‐crosslinkable nanopatch (pCNP). By forming a protective barrier over injured mesothelium, the pCNP is highly effective and safe in preventing peritoneal excision adhesion in a rodent model. This work presents a novel approach to preventing peritoneal adhesion with nanomaterials.

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Keywords: abdominal surgery, biological targeting, nanomaterials, peritoneal adhesion, photo‐crosslinking


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