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. Author manuscript; available in PMC: 2019 Oct 18.
Published in final edited form as: Cell. 2018 Oct 18;175(3):835–847.e25. doi: 10.1016/j.cell.2018.09.056

Figure 5: Inferred transcription parameters are tightly constrained across gap genes.

Figure 5:

(A,B) Inferred Pol II initiation rate kini (A), and promoter mean occupancy n (B) for all genes across AP position.

(C,D) Inferred on-rate kon (C) and off-rate koff (D) as a function of mean occupancy n for all genes. Solid black lines represent the global trend using the mean value of τn (see formula in inset).

(E) Inferred switching correlation time τn as a function of mean occupancy n for all genes with a mean value of τ¯n=3.0±1.2 min (dashed line).

(F,G) Inferred burst size b (F) and burst frequency f (G) as a function of the mean occupancy n. Solid black lines represent the global trend using the mean value of kini and τn (see formula in inset).

Color code as in Figure 1C. Error bars are the 10 to 90th percentiles of the posterior distribution. See also Figure S6.